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"The gene, called fruitless (fru), is the first shown to control a complex set of behaviors in an animal.
"Biologists have known since the 1970s that flies with a mild mutation in fru are bisexual, courting both males and females." (Science.org)
Early work refers to the gene as fruity, an apparent pun on both the common name of D. melanogaster, the fruit fly, as well as a slang word for homosexual. As social attitudes towards homosexuality changed, fruity came to be regarded as offensive, or at best, not politically correct. Thus, the gene was re-dubbed fruitless, alluding to the lack of offspring produced by flies with the mutation.[10] However, despite the original name and a continuing history of misleading inferences by the popular media, fruitless mutants primarily show defects in male-female courtship, though certain mutants cause male-male or female-female courtship." Wikipedia